Last edited by Tam
Monday, April 27, 2020 | History

8 edition of Formulation, Characterization, and Stability of Protein Drugs found in the catalog.

Formulation, Characterization, and Stability of Protein Drugs

Case Histories (Pharmaceutical Biotechnology) (Pharmaceutical Biotechnology)

by

  • 350 Want to read
  • 23 Currently reading

Published by Springer Verlag .
Written in English

    Subjects:
  • Pharmaceutical Chemistry,
  • Medical,
  • Medical / Nursing,
  • Science/Mathematics,
  • Pharmacy,
  • Science / Biological Sciences,
  • Medical / Pharmacology,
  • Medical : Pharmacy,
  • Peptide drugs,
  • Pharmacology,
  • Protein drugs,
  • Proteins,
  • analysis

  • Edition Notes

    ContributionsRodney Pearlman (Editor), Y. John Wang (Editor)
    The Physical Object
    FormatHardcover
    Number of Pages460
    ID Numbers
    Open LibraryOL9541875M
    ISBN 100306453320
    ISBN 109780306453328


Share this book
You might also like
veterinary medical team handbook

veterinary medical team handbook

text-book on roofs and bridges

text-book on roofs and bridges

History of Jewish coinage, and of money in the Old and New Testament.

History of Jewish coinage, and of money in the Old and New Testament.

great prophecies of China.

great prophecies of China.

Sly Fox and Red Hen (Read It Yourself Level 2)

Sly Fox and Red Hen (Read It Yourself Level 2)

Study of occupational therapy teaching resources in the United Kingdom.

Study of occupational therapy teaching resources in the United Kingdom.

Native American literature

Native American literature

Treasures Practice Book O Grade 2

Treasures Practice Book O Grade 2

Interpreting and Collecting Fragments of Medieval Books

Interpreting and Collecting Fragments of Medieval Books

Goldwing GL1800 Honda

Goldwing GL1800 Honda

Sir Peter Scott at 80.

Sir Peter Scott at 80.

A History of American Magazines, Volume IV

A History of American Magazines, Volume IV

Elastic instability

Elastic instability

Color

Color

old furniture book

old furniture book

On the lamented death of Her Most Excellent Majesty, Queen Mary

On the lamented death of Her Most Excellent Majesty, Queen Mary

Rawls linguistic analogy

Rawls linguistic analogy

Formulation, Characterization, and Stability of Protein Drugs Download PDF EPUB FB2

Leading scientists offer detailed profiles of ten protein drugs currently in development. The case histories of these important new compounds are described from the perspective of their formulation, characterization, and stability. This ready reference also features recent data and an abundance.

Leading scientists offer detailed profiles of ten protein drugs currently in development. The case histories of these important new compounds are described from the perspective of their formulation, characterization, and stability.

This ready reference also features recent data and an abundance of previously unpublished : Hardcover. Leading scientists offer detailed profiles of ten protein drugs currently in development. The case histories of these important new compounds are described from the perspective of their formulation, characterization, and stability.

This ready reference also features recent data and an abundance of previously unpublished information. The in-depth coverage includes a highly useful compendium of. Leading scientists offer detailed profiles of ten protein drugs currently in development.

The case histories of these important new compounds are described from the perspective of their formulation, characterization, and stability. This ready reference also features recent data and an abundance of previously unpublished information.

Formulation, Characterization, and Stability of Protein Drugs, Rodney Pearlman and Y. John Wang, eds., Plenum Press, New York, Michael F. Powell. INTRODUCTION. The accurate prediction of protein stability under pharmaceutical formulation conditions is one of the more challenging goals in protein formulation.

Protein Stability and Characterization. Native ESI MS also allows the interactions of protein drugs with their therapeutic targets and other physiological partners to be monitored using simple Author: Atanas Koulov. This volume attemptsto provide the formulation scientist with casehistories involving the use of therapeutic proteins and peptides that have been mar­ keted or are under clinical testing.

In previous volumes of this series,funda­ mental theories and principles ofprotein characterization and stability were presented in depth by researchers in their fieldsofexpertise.5/5(1).

Stability and Characterization of Protein and Peptide Drugs by Rodney Pearlman,available at Book Depository with free delivery worldwide. Nonionic surfactants are often used in protein formulations to reduce interfacial stress and prevent protein denaturation, aggregation, and adsorption loss (Lee et al., ).Thus, if interfacial stress is a stability concern for a particular protein molecule, then use of a nonionic surfactant is a good first step in mitigating this problem.

Nguyen TH, Ward C () Stability characterization and formulation development of Alteplase, a recombinant tissue type plasminogen activator. In: Wang YJ, Pearlman R (eds) Stability and characterization of protein and peptide drugs: Case Histories, Plenum Press, New York, pp 91 – Author: C.

Middaugh, R. Pearlman. Parenteral formulations of proteins and peptides: stability and stabilizers Article (PDF Available) January with 1, Reads How we measure 'reads'. Stability and Characterization of Protein and Peptide Drugs Stability and Characterization of Protein and Peptide Drugs Case Histories.

Editors: Pearlman, Rodney, Wang, Y. John (Eds.) Stability Characterization and Formulation Development of Alteplase. SCREENING APPROACH TO THE CHARACTERIZATION AND FORMULATION OF BIOPHARMACEUTICALS Sangeeta B.

Joshi, Akhilesh Bhambhani, Yuhong Zeng, and C. Russell Middaugh 9 FLUORESCENCE AND PHOSPHORESCENCE METHODS TO PROBE PROTEIN STRUCTURE AND STABILITY IN ICE: THE CASE OF AZURIN Giovanni B. Strambini 10. Stability and Characterization of Protein and Peptide Drugs Case And Stability of Protein Drugs book.

Editors (view affiliations) Y. John Wang; Rodney Pearlman Search within book. Front Matter. Pages i-xxi. PDF. Michael J. Hageman. Pages Stability Characterization and Formulation Development of Alteplase, a Recombinant Tissue Plasminogen Activator.

Tue H. Drugs can be administered via various routes, and the selection of a route depends on the drug characteristics, site of action, duration of action, condition of the patient, and environmental factors such as pH, presence of enzymes, and metabolization of the drug.

The various routes that are used for administering drugs are shown in Fig. Author: Seyedehsara Masoomi Dezfooli, Lari Dkhar, Abbey Long, Hamideh Gholizadeh, Soniya Mohammadi, Carol An. Formulation, Characterization, and Stability of Protein Drugs Case Histories edited by Rodney Pearlman.

In Formulation, Characterization, and Stability of Protein Drugs, leading scientists offer detailed profiles of ten protein drugs currently in case histories of these important new compounds are described from the perspective of their formulation, characterization, and stability.

ISBN: OCLC Number: Notes: Continues: Stability and characterization of protein and peptide drugs. c Description. Get this from a library. Formulation, characterization, and stability of protein drugs: case histories.

[Rodney Pearlman; Y John Wang;] -- "This volume represents the second compilation of case histories of formulation, stabilization, and characterization of protein drugs. The first volume, Stability and Characterization of Protein and.

This course is intended for those currently working in the field and presumes a basic working knowledge of protein structure. This course is intended for those currently working in the field and presumes a basic working knowledge of protein structure.

Course Programme. Overview of Formulation Strategies and Principles. Physical Stability of. Rodney Pearlman is the author of Formulation, Characterization, and Stability of Protein Drugs ( avg rating, 2 ratings, 0 reviews, published ), S 3/5(2).

A real-world guide to the production and manufacturing of biopharmaceuticals. While much has been written about the science of biopharmaceuticals, there is a need for practical, up-to-date information on key issues at all stages of developing and manufacturing commercially viable biopharmaceutical drug.

It discusses the characterization and chemical stability of peptides and proteins, before moving on to formulation, detailing peptides and proteins in solution and as suspensions, as well as lyophilized peptide and protein products.

There follows a case study on drug delivery systems for. Stages and timeline. Formulation studies involve developing a preparation of the drug which is both stable and acceptable to the patient.

For orally administered drugs, this usually involves incorporating the drug into a tablet or a is important to make the distinction that a tablet contains a variety of other potentially inert substances apart from the drug itself, and studies have. c) Solid state stability: The primary objective of this study is investigation and identification of stable storage condition for drug in the solid state and identification of compatible excipients for a formulation.

In all solid dosage formulation there will be some free moisture contributed by excipients as well as the drug and certainly in. The optimized formulation showed % drug release within 20 min, which correlated with the predicted data. The optimized formulation showed peppas as a best fit model with r 2 value of The release rate followed the nonfickian diffusion mechanism as its n.

Many new drugs are based on peptide or protein recombinant technology going hand in hand with more traditional pharmaceutical formulation. In order to develop products with optimal characters, it is important to give scientists interdisciplinary knowledge and a thorough understanding of the complex nature of pharmaceutical formulation of.

Stability and Characterization of Protein and Peptide Drugs | This volume attemptsto provide the formulation scientist with casehistories involving the use of therapeutic proteins and peptides that have been mar- keted or are under clinical testing.

In previous volumes of this series, funda- mental theories and principles ofprotein characterization and stability were presented in depth by.

Nanoparticles (NPs) based on the polymer poly (lactide-co-glycolide) acid (PLGA) have been widely studied in developing delivery systems for drugs and therapeutic biomolecules, due to the biocompatible and biodegradable properties of the PLGA.

In this work, a synthesis method for bone morphogenetic protein (BMP-2)-loaded PLGA NPs was developed and optimized, in order to carry out and control Cited by: 1. Formulation Characterization and Stability of Protein Drugs Case Histories. of Share & Embed.

In this study, we developed an efficient PEG-lipid-based polymeric micelle formulation with enhanced drug solubility and stability for cabozantinib delivery.

DSPE-PEG micelles encapsulating cabozantinib were prepared by a thin-film rehydration method followed by a lyophilization process to generate the dry dosage by: 7. Protein Formulation and Delivery - CRC Press Book 1. Overview of Protein Formulation and Delivery 1 James Wright 2.

Chemical Considerations in Protein and Peptide Stability 7 Paul M. Bummer 3. Physical Considerations in Protein and Peptide Stability 43 Sandy Koppenol 4. Title:Characterization of Particulate Drug Delivery Systems for Oral Delivery of Peptide and Protein Drugs VOLUME: 21 ISSUE: 19 Author(s):Philip Carsten Christophersen, Mathias Fano, Lasse Saaby, Mingshi Yang, Hanne Mørck Nielsen and Huiling Mu Affiliation:Department of Pharmacy, Universitetsparken 2, Copenhagen; Keywords:Oral drug delivery, peptide/protein drugs, particulate delivery Cited by:   Buy the Paperback Book Stability and Characterization of Protein and Peptide Drugs: Case Histories by Rodney Pearlman atCanada's largest bookstore.

Free shipping and pickup in store on eligible orders. Preformulation is a group of studies that focus on the physicochemical properties of a new drug candidate that could affect the drug performance and the development of a dosage form. This could provide important information for formulation design or support the need for molecular modification.

Every drug has intrinsic chemical and physical properties which has been consider before development. This volume attemptsto provide the formulation scientist with casehistories involving the use of therapeutic proteins and peptides that have been mar- keted or are under clinical testing.

In previous volumes of this series, funda- mental theories and principles ofprotein characterization and stability were presented in depth by researchers in 5/5(1). It isthe first time a collection of this sort has been made accessibleto the formulation scientists involved in devel- oping protein and peptide products.

Although each chapter in this volume focuses primarily on the charac- terization and stability of a specific molecule, each has unique : Rodney Pearlman.

Drug Delivery Nanoparticles Formulation and Characterization, edited by Yashwant Pathak and Deepak Thassu 6. edited by Yashwant Pathak Sullivan University College of Pharmacy Louisville, Kentucky, USA Deepak Thassu PharmaNova, Inc.

Victor, New York, USA Drug Delivery Nanoparticles Formulation and Characterization 7. The second edition of Protein Formulation and Delivery presents an updated review of recent research in the formulation and delivery of therapeutic proteins and peptides.

The book contains expanded sections about protein characterization and formulation and several new. Therefore, the formulation of emulsions needs to be considered and selected according to the final product composition and industrial processing required.

Besides the colloidal stability of beverage emulsions, other aspects such as the chemical stability of the functional ingredients and their health benefits after being digested need by: 4.

Publication date Note Also available in print edition. Format Mode of access: World Wide Web. ISBN (v. 1: e-book: PDF) (v. 2: e-book: PDF). In formulation development, the combination of formulation components creates the formulation space, and the data obtained from stability studies create the formulation stability space.

In cases where the number of formulations is too large to screen, a design of experiment (DOE) approach can significantly save limited by: Protein stability prediction related to thermodynamics degradation studies of biologics to understand how some of the stress conditions affect the secondary structure of the protein in the formulation.

This talk focuses on the DCDR spectroscopy and its capabilities for effective characterization of changes in secondary structure of protein.8. An Empirical Phase Diagram/ High Throughput Screening Approach to the Characterization and Formulation of Biopharmaceuticals (Sangeeta B.

Joshi-- Akhilesh Bhambhani-- Yuhong Zeng-- and C. Russell Middaugh). 9. Fluorescence and Phosphorescence Methods to Probe Protein Structure and Stability in Ice: the Case of Azurin (Giovanni Strambini).